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Frankfurt is the financial and business center of Germany and the largest city in the German province of Hesse. It is renowned for its modern skyline and the busiest German airport. The city is the birthplace of the famous writer Johann Wolfgang von Goethe, whose former home is now the Goethe House Museum. With a population of 746,878, it is the fifth-largest city in Germany, following Berlin, Hamburg, Munich, and Cologne. Frankfurt is at the heart of the larger Rhine-Main Metropolitan Region, which has a population of 5.5 million, making it Germany's second-largest metropolitan region after the Rhine-Ruhr Region. Frankfurt is an alpha world city and a global hub for trade, culture, education, tourism, and transportation. It hosts numerous international and European corporate headquarters. Frankfurt Airport is one of the world's busiest. The city is the leading financial center on the European continent, housing the European Central Bank, Deutsche Bundesbank, Frankfurt Stock Exchange, Deutsche Bank, DZ Bank, KfW, and Commerzbank, as well as various cloud and fintech startups. The city's economy is also bolstered by sectors like automotive, technology and research, services, consulting, media, and creative industries. Frankfurt's DE-CIX is the world's largest internet exchange point. Messe Frankfurt is one of the world's largest trade fairs, hosting significant events such as the Frankfurt Motor Show, the world's largest motor show, the Music Fair, and the Frankfurt Book Fair, the world's largest book fair.